Chopped Biscuit Pizza Casserole

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Imagine everything you love about pizza — gooey cheese, savory pepperoni, zesty sauce — baked into one bubbly, golden-brown casserole. Now, add in chunks of soft, buttery biscuit dough that soak up all that delicious flavor, and you’ve got a weeknight dinner winner. This Chopped Biscuit Pizza Casserole is comfort food at its easiest and tastiest, perfect for feeding a hungry crowd or serving up a quick family dinner.

The real beauty of this dish is how effortlessly it comes together. Just chop, mix, bake, and serve. It’s a fun twist on traditional pizza that skips the dough rolling and leans into simplicity. Whether you’re hosting a casual get-together, looking for a kid-approved meal, or just need a no-fuss dinner idea, this casserole delivers all the cheesy, meaty satisfaction of your favorite pie — with half the effort.

Why You’ll Love This Chopped Biscuit Pizza Casserole

• It’s incredibly easy to prepare — great for busy weeknights.
• Customizable with your favorite pizza toppings.
• Crowd-pleasing and family-friendly.
• Comfort food at its finest with minimal cleanup.
• Freezer-friendly and great for meal prepping.

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Preparation Phase & Tools to Use

To make the Chopped Biscuit Pizza Casserole, you’ll need a few basic kitchen essentials. Start with a sharp knife and cutting board for chopping the biscuits into bite-sized pieces. A large mixing bowl will help combine all the ingredients evenly. Use a silicone spatula or wooden spoon to gently fold everything together without overmixing.

You’ll also need a standard 9×13-inch baking dish to ensure even cooking and a bubbly golden top. For easier cleanup and smoother serving, consider greasing the dish with cooking spray or a little butter. Finally, an oven mitt and a cooling rack are useful for safely handling the hot dish straight from the oven.

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Preparation Tips

To make this dish shine, start with fresh, refrigerated biscuit dough — not the flaky layered kind, but the homestyle variety works best. When chopping the biscuits, aim for roughly 1-inch pieces to ensure even baking and better texture. Lightly toss the dough with sauce, cheese, and toppings so that every bite is flavorful and well-coated.

Avoid overloading the casserole with too many toppings, which can lead to soggy results. If you’re using veggies like mushrooms or bell peppers, consider sautéing them first to reduce moisture. And don’t skimp on cheese — a mix of mozzarella and cheddar adds melty richness. For extra crispiness, broil the casserole for the last 2-3 minutes of baking.

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Ingredients for this Chopped Biscuit Pizza Casserole

• 2 cans (16 oz total) refrigerated homestyle biscuit dough
• 1 1/2 cups shredded mozzarella cheese
• 1/2 cup shredded cheddar cheese (optional for extra richness)
• 1 cup pizza sauce or marinara sauce
• 25–30 slices of pepperoni (or more to taste)
• 1/2 teaspoon Italian seasoning
• 1/4 teaspoon garlic powder
• 1 tablespoon olive oil or melted butter (optional, for brushing top)
• Fresh parsley or basil for garnish (optional)
• Optional toppings: cooked sausage, sautéed mushrooms, diced bell peppers, black olives, red onions

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Step 1: Preheat and Prepare the Oven

Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish with cooking spray or butter to prevent sticking and ensure an easy cleanup.

Step 2: Chop the Biscuit Dough

Open the biscuit cans and separate the dough. Using a sharp knife or kitchen scissors, cut each biscuit into quarters or 1-inch bite-sized pieces. Transfer the chopped dough to a large mixing bowl.

Step 3: Mix with Sauce and Seasonings

Add the pizza sauce to the bowl with the biscuit pieces. Sprinkle in the Italian seasoning and garlic powder, then gently stir to coat all the dough evenly. This helps infuse the pizza flavor into every bite.

Step 4: Add Cheese and Toppings

Fold in the mozzarella cheese (and cheddar if using) along with about half the pepperoni slices. If you’re including additional toppings like cooked sausage or sautéed vegetables, mix them in now. Stir gently to distribute evenly without breaking apart the dough pieces.

Step 5: Transfer to Baking Dish

Pour the entire biscuit mixture into the prepared baking dish. Spread it out into an even layer. Arrange the remaining pepperoni slices on top and optionally brush the top with melted butter or olive oil for a golden finish.

Step 6: Bake Until Golden and Bubbly

Place the dish in the preheated oven and bake for 30–35 minutes, or until the top is golden brown and the cheese is bubbly. You can insert a toothpick into the center to check if the dough is fully cooked.

Step 7: Optional Broil for Extra Crispiness

If you prefer a crispy top, switch the oven to broil for the last 2–3 minutes. Keep a close eye to avoid burning. This step gives the pepperoni and cheese a satisfying finish.

Step 8: Cool Slightly and Garnish

Once baked, remove from the oven and let it cool for about 5 minutes. Garnish with freshly chopped parsley or basil for a pop of color and fresh flavor.

Step 9: Serve and Enjoy

Scoop generous portions onto plates and serve warm. Pair with a crisp green salad, garlic bread, or enjoy it as a standalone meal that satisfies every pizza craving.

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Notes

This Chopped Biscuit Pizza Casserole is a fun, versatile recipe that works with nearly any combination of toppings. If you’re using ingredients with high moisture content (like mushrooms or spinach), sauté or drain them first to avoid soggy results. It’s also a great dish for using up leftover meats or veggies — just chop and fold them in with the biscuit dough and sauce.

You can use either store-bought pizza sauce or marinara — both work well. For a more robust flavor, consider adding a pinch of crushed red pepper flakes or a few spoonfuls of grated Parmesan cheese to the mix before baking. It’s also totally fine to make this meatless; just load it up with roasted veggies instead.

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Watch Out for These Mistakes While Cooking

• Using flaky biscuits instead of homestyle dough can result in uneven baking and texture.
• Skipping the pre-grease step might cause the casserole to stick to the dish.
• Overcrowding with toppings can make the dish soggy and cause undercooked dough.
• Not checking doneness with a toothpick could lead to raw dough in the center.
• Skipping the broil step means missing out on that perfect golden, crisp finish.

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Storage Instructions

Let the casserole cool completely before storing. Leftovers can be kept in an airtight container in the refrigerator for up to 3 days. Reheat in the oven at 350°F for 10–15 minutes or microwave individual portions for about 1–2 minutes. To freeze, wrap individual portions or the whole baked dish tightly in foil or plastic wrap and freeze for up to 2 months. Thaw overnight in the fridge before reheating.

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Estimated Nutrition (Per Serving – Based on 8 Servings)

• Calories: 340
• Protein: 12g
• Carbohydrates: 28g
• Fat: 20g
• Saturated Fat: 8g
• Unsaturated Fat: 10g
• Trans Fat: 0g
• Cholesterol: 35mg
• Sodium: 730mg
• Sugar: 3g
• Fiber: 1g

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Frequently Asked Questions

What kind of biscuit dough should I use?

Use refrigerated homestyle biscuit dough — not the flaky layered variety, which bakes differently and can result in uneven texture.

Can I make this casserole ahead of time?

Yes, you can assemble it ahead and refrigerate for up to 24 hours before baking. Just add 5–10 extra minutes to the bake time if it’s going into the oven cold.

Can I make it vegetarian?

Absolutely! Swap out the pepperoni for veggies like mushrooms, bell peppers, and olives. Be sure to sauté any high-moisture vegetables first.

How do I know when it’s done baking?

The top should be golden and bubbly, and a toothpick inserted into the center should come out clean. If not, give it a few more minutes and check again.

Can I use different cheeses?

Yes! Try provolone, cheddar, or a pizza blend. Mozzarella gives it that classic stretch, but mixing in other cheeses adds flavor depth.

What should I serve it with?

A simple green salad, garlic bread, or roasted veggies pair well. It’s hearty enough to serve as a complete meal on its own, too.

Can I freeze this casserole?

Yes, after baking and cooling completely. Wrap well and freeze for up to 2 months. Thaw overnight and reheat in the oven until warmed through.

Is this kid-friendly?

Very! Kids love the cheesy, pepperoni-packed flavor and fun biscuit texture. It’s also a great dish to let them help assemble.

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Conclusion

Chopped Biscuit Pizza Casserole is a delicious twist on pizza night, offering everything you love about pizza in a warm, comforting casserole form. It’s easy to throw together, endlessly customizable, and guaranteed to be a hit whether you’re serving picky eaters, a hungry family, or a potluck crowd. With just a few simple ingredients and steps, this recipe delivers maximum flavor with minimal effort — a weeknight win that will definitely make it into your regular dinner rotation.

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